FND Biotech provides the same FNDs used in Dr. H.-C. Chang's publications.

Review Articles
  1. W. W.-W. Hsiao, Y. Y. Hui, P.-C. Tsai, and H.-C. Chang, "Fluorescent nanodiamond: A versatile tool for long-term cell tracking, super-resolution imaging, and nanoscale temperature sensing," Acc. Chem. Res. 49, 400-407 (2016). Link
  2. W. W.-W. Hsiao, H.-H. Lin, F.-J. Hsieh, and H.-C. Chang, "Surface-modified nanodiamonds," in Carbon Nanomaterials Sourcebook: Graphene, Fullerenes, Nanotubes, and Nanodiamonds, Vol. I, ed. K. D. Sattler (CRC Press, 2016), Chap. 22, p. 517-533.
  3. W. W.-W. Hsiao, H.-H. Lin, and H.-C. Chang, "Diamond nanoparticles for drug delivery and monitoring," in Springer Series on Chemical Sensors and Biosensors, eds. C. Nebel and C. Kranz (Springer, Morwell, 2016), in press.
  4. Y. Y. Hui, W. W.-W. Hsiao, S. Haziza, M. Simonneau, F. Treussart*, and H.-C. Chang*, "Single particle tracking of fluorescent nanodiamonds in cells and organisms," Curr. Opin. Solid State Mater. Sci. (2016) DOI: 10.1016/j.cossms.2016.04.002.
  5. Y. Y. Hui and H.-C. Chang, "Recent developments and applications of nanodiamonds as versatile bioimaging agents," J. Chin. Chem. Soc. 61, 67-76 (2014).Link
  6. Y. Y. Hui, C.-L. Cheng, and H.-C. Chang, "Nanodiamonds for optical bioimaging," J. Phys. D: Appl. Phys. 43, 374021 (2010).Link
  7. C.-C. Wu, C.-C. Han, and H.-C. Chang, "Applications of surface-functionalized diamond nanoparticles for mass-spectrometry-based proteomics," J. Chin. Chem. Soc. 57, 582_594 (2010). Link
  8. V. Vaijayanthimala and H.-C. Chang, "Functionalized fluorescent nanodiamonds for biomedical applications," Nanomed. 4, 47_55 (2009).Link
  1. T.-C. Hsu, K.-K. Liu, H.-C. Chang, E. Hwang, and J.-I. Chao, "Labeling of neuronal differentiation and neuron cells with biocompatible fluorescent nanodiamonds," Sci. Rep. 4, 5004 (2014). Link
  2. H.-C. Li, F.-J. Hsieh, C.-P. Chen, M.-Y. Chang, P. C. H. Hsieh, C.-C. Chen, S.-U. Hung, C.-C. Wu, and H.-C. Chang, "The hemocompatibility of oxidized diamond nanocrystals for biomedical applications," Sci. Rep. 3, 3044 (2013).Link
  3. V. Vaijayanthimala, P.-Y. Cheng, S.-H. Yeh, K.-K. Liu, C.-H. Hsiao, J.-I Chao, and H.-C. Chang, "The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent," Biomaterials 33, 7794_7802 (2012).Link
  4. V. Vaijayanthimala, Y.-K. Tzeng, H.-C. Chang, and C.-L. Li, "The biocompatibility of fluorescent nanodiamonds and their mechanism of cellular uptake," Nanotechnology 20, 425103 (2009).Link
FND Production
  1. L.-J. Su, C.-Y. Fang, Y.-T. Chang, K.-M. Chen, Y.-C. Yu, J.-H. Hsu, and H.-C. Chang, "Creation of high density ensembles of nitrogen-vacancy centers in nitrogen-rich type Ib nanodiamonds," Nanotechnology 24, 315702 (2013)Link
  2. N. Mohan, Y.-K. Tzeng, L. Yang, Y.-Y. Chen, Y. Y. Hui, C.-Y. Fang, and H.-C. Chang, "Sub-20-nm fluorescent nanodiamonds as photostable biolabels and fluorescence resonance energy transfer donors," Adv. Mater. 22, 842_847 (2010).Link
  3. T.-L. Wee, Y.-W. Mau, C.-Y. Fang, H.-L. Hsu, C.-C. Han, and H.-C. Chang, "Preparation and characterization of green fluorescent nanodiamonds for biological applications,"Diamond Relat. Mater. 18, 567_573 (2009).Link
  4. Y.-R. Chang, H.-Y. Lee, K. Chen, C.-C. Chang, D.-S. Tsai, C.-C. Fu, T.-S. Lim, Y.-K. Tzeng, C.-Y. Fang, C.-C. Han, H.-C. Chang, and W. Fann, "Mass production and dynamic imaging of fluorescent nanodiamonds," Nature Nanotech. 3, 284_288 (2008).Link
  5. S.-J. Yu, M.-W. Kang, H.-C. Chang, K.-M. Chen, and Y.-C. Yu, "Bright fluorescent nanodiamonds: No photobleaching and low cytotoxicity," J. Am. Chem. Soc. 127, 17604_17605 (2005).Link
Photoluminescence Imaging
  1. Y. Y. Hui, L.-J. Su, O. Y. Chen, Y.-T. Chen, T.-M. Liu, and H.-C. Chang, "Wide-field imaging and flow cytometric analysis of cancer cells in blood by fluorescent nanodiamond labeling and time gating," Sci. Rep. 4, 5574 (2014).
  2. Z. Chu, S. Zhang, B. Zhang, C. Zhang, C.-Y. Fang, I. Rehor, P. Cigler, H.-C. Chang, G. Lin, R. Liu, and Q. Li, "Unambiguous observation of shape effects on cellular fate of nanoparticles," Sci. Rep. 4, 4495 (2014).Link
  3. B.-M. Chang, H.-H. Lin, L.-J. Su, W.-D. Lin, R.-J. Lin, Y.-K. Tzeng, R. T. Lee, Y. C. Lee, A. L. Yu, and H.-C. Chang, "Highly fluorescent nanodiamonds protein-functionalized for cell labeling and targeting," Adv. Funct. Mater. 23, 5737-5745 (2013).Link
  4. T.-J. Wu, Y.-K. Tzeng, W.-W. Chang, C.-A. Cheng, Y. Kuo, C.-H. Chien, H.-C. Chang, and J. Yu, "Tracking the engraftment and regenerative capabilities of transplanted lung stem cells using fluorescent nanodiamonds," Nature Nanotech. 8, 682-689 (2013).Link
  5. Y. Kuo, T.-Y. Hsu, Y.-C. Wu, and H.-C. Chang, "Fluorescent nanodiamond as a probe for the intercellular transport of proteins in vivo," Biomaterials 34, 8352_8360 (2013).Link
  6. C.-Y. Fang, V. Vaijayanthimala, C.-A. Cheng, S.-H. Yeh, C.-F. Chang, C.-L. Li, and H.-C. Chang, "The exocytosis of fluorescent nanodiamond and its use as a long-term cell tracker," Small 7, 3362_3370 (2011). LinkN. Mohan, C.-S. Chen, H.-H. Hsieh, Y.-C. Wu, and H.-C. Chang, "In vivo imaging and toxicity assessments of fluorescent nanodiamonds in Caenorhabditis elegans," Nano Lett.10, 3692_3699 (2010). Link
  7. B. Zhang, Y. Li, C.-Y. Fang, C.-C. Chang, C.-S. Chen, Y.-Y. Chen, and H.-C. Chang, "Receptor-mediated cellular uptake of folate-conjugated fluorescent nanodiamonds: A combined ensemble and single-particle study," Small 5, 2716_2721 (2009).Link
  8. C.-C. Fu, H.-Y. Lee, K. Chen, T.-S. Lim, H.- Y. Wu, P.-K. Lin, P.-K. Wei, P.-H. Tsao, H.-C. Chang, and W. Fann, "Characterization and application of single fluorescent nanodiamonds as cellular biomarkers," Proc. Natl. Acad. Sci. USA 104, 727_732 (2007).Link
Two-Photon Excitation Imaging
  1. Y. Y. Hui, B. Zhang, Y.-C. Chang, C.-C. Chang, H.-C. Chang, J.-H. Hsu, K. Chang, and F.-H. Chang, "Two-photon fluorescence correlation spectroscopy of lipid-encapsulated fluorescent nanodiamonds in living cells," Opt. Express 18, 5896_5905 (2010). Link
  2. T.-L. Wee, Y.-K. Tzeng, C.-C. Han, H.-C. Chang, W. Fann, J.-H. Hsu, K.-M. Chen, and Y.-C. Yu, "Two-photon excited fluorescence of nitrogen-vacancy centers in proton-irradiated type Ib diamond," J. Phys. Chem. A 111, 9379_9386 (2007).Link
Superresolution Imaging
  1. X. Yang, Y.-K. Tzeng, Z. Zhu, Z. Huang, X. Chen, Y. Liu, H.-C. Chang, L. Huang, W.-D. Li, and P. Xi, "Sub-diffraction imaging of nitrogen-vacancy centers in diamond by stimulated emission depletion and structured illumination," RSC Adv. 4, 11305-11310 (2014).Link
  2. Y. Y. Hui, Y.-C. Lu, L-J. Su, C.-Y. Fang, J.-H. Hsu, and H.-C. Chang, "Tip-enhanced sub-diffraction fluorescence imaging of nitrogen-vacancy centers in nanodiamonds," Appl. Phys. Lett. 102, 013102 (2013).Link
  3. Y.-K. Tzeng, O. Faklaris, B.-M. Chang, Y. Kuo, J.-H. Hsu, and H.-C. Chang, "Superresolution imaging of albumin-conjugated fluorescent nanodiamonds in cells by stimulated emission depletion," Angew. Chem. Int. Ed. 50, 2262_2265 (2011). Link
  4. M. Yamanaka, Y.-K. Tzeng, S. Kawano, N. I. Smith, S. Kawata, H.-C. Chang, and K. Fujita, "SAX microscopy with fluorescent nanodiamond probes for high-resolution fluorescence imaging," Biomed. Opt. Express 2, 1946_1954 (2011).Link
Photoacoustic Imaging
  1. T. Zhang, H. Cui, C.-Y. Fang, L.-J. Su, H.-C. Chang, X. Yang, and M. L. Forrest, "Photoacoustic contrast imaging of biological tissues with nanodiamonds fabricated for high near-infrared absorbance," J. Biomed. Opt. 18, 026018 (2013).Link
  2. B. Zhang, C.-Y. Fang, C.-C. Chang, R. Peterson, S. Maswadi, R. D. Glickman, H.-C. Chang, and J. Y. Ye, "Photoacoustic emission from fluorescent nanodiamonds enhanced with gold nanoparticles," Biomed. Opt. Express 3, 1662_1669 (2012).Link
Cathodoluminescence Imaging
  1. Y. Nawa, W. Inami, S. Lin, Y. Kawata, S. Terakawa, C.-Y. Fang, and H.-C. Chang, "Multicolor imaging of fluorescent nanodiamonds in living HeLa cells using direct electron-beam excitation," ChemPhysChem 15, 721-726 (2014).Link
  2. L. H. G. Tizei, S. Meuret, S. Nagarajan, F. Treussart, C.-Y. Fang, H.-C. Chang, and M. Kociak, "Spatially and spectrally resolved cathodoluminescence with fast electrons: A tool for background subtraction in luminescence intensity second-order correlation measurements applied to subwavelength inhomogeneous diamond nanocrystals," Phys. Status Solidi A 210, 2060-2065 (2013).Link
ND-Based Solid Phase Extraction
  1. C.-C. Hsieh, J. Y. Guo, S.-U. Hung, R. Chen, Z. Nie, H.-C. Chang, and C.-C. Wu, "Quantitative analysis of oligosaccharides derived from sulfated glycosaminoglycans by nanodiamond-based affinity purification and MALDI MS," Anal. Chem. 85, 4342_4349 (2013).Link
  2. C.-K. Chang, C.-C. Wu, Y.-S. Wang, and H.-C. Chang, "Selective extraction and enrichment of multi-phosphorylated peptides using polyarginine-coated diamond nanoparticles," Anal. Chem. 80, 3791_3797 (2008).Link
  3. Y.-K. Tzeng, C.-C. Chang, C.-N. Huang, C.-C. Wu, C.-C. Han, and H.-C. Chang, "Facile MALDI-MS analysis of neutral glycans in NaOH-doped matrices: Microwave-assisted deglycosylation and one-step purification with diamond nanoparticles," Anal. Chem. 80, 6809_6814 (2008).Link
  4. T. T. B. Ngyuen, H.-C. Chang, and V. W.-K. Wu, "Adsorption and hydrolytic activity of lysozyme on diamond nanocrystallites," Diamond Relat. Mater. 16, 872_876 (2007).Link
  5. S. Sabu, F.-C. Yang, Y.-S. Wang, W.-H. Chen, H.-C. Chang, and C.-C. Han, "Peptide analysis: Solid phase extraction-elution on diamond (SPEED) combined with atmospheric pressure MALDI-FTICR mass spectrometry," Anal. Biochem. 367, 190_200 (2007).Link
  6. W.-H. Chen, S.-C. Lee, S. Sabu, H.-C. Fang, S.-C. Chung, C.-C. Han, and H.-C. Chang, "Solid phase extraction and elution on diamond (SPEED): A fast and general platform for proteome analysis with mass spectrometry," Anal. Chem. 78, 4228_4234 (2006).Link
  7. X. L. Kong, L. C. L. Huang, S.-C. V. Liau, C.-C. Han, and H.-C. Chang, "Polylysine-coated diamond nanocrystals for MALDI-TOF mass analysis of DNA oligonucleotides," Anal. Chem. 77, 4272_4277 (2005).Link
  8. X. L. Kong, L. C. L. Huang, C.-M. Hsu, W.-H. Chen, C.-C. Han, and H.-C. Chang, "High-affinity capture of proteins by diamond nanoparticles for mass spectrometric analysis,"Anal. Chem. 77, 259_265 (2005). Link
  9. L. C. L. Huang and H.-C. Chang, "Adsorption and immobilization of cytochrome c on nanodiamonds," Langmuir 20, 5879_5884 (2004).Link
  1. C. P. Epperla, O. Y. Chen, and H.-C. Chang*, "Gold/diamond nanohybrids may reveal how hyperlocalized hyperthermia kills cancer cells," Nanomedicine 11, 443-445 (2016).
  2. P.-C. Tsai, O. Y. Chen, Y.-K. Tzeng, Y. Y. Hui, J. Y. Guo, C.-C. Wu, M.-S. Chang, and H.-C. Chang*, "Gold/diamond nanohybrids for quantum sensing applications," EPJ Quantum Technol. 2, 19 (2015).
  3. H. Kaupp, C. Deutsch, H.-C. Chang, J. Reichel, T. W. Hänsch, and D. Hunger, "Scaling laws of the cavity enhancement for nitrogen-vacancy centers in diamond," Phys. Rev. A 88, 053812 (2013). Link
  4. A. Ermakova, G. Pramanik, J.-M. Cai, G. Algara-Siller, U. Kaiser, T. Weil, Y.-K. Tzeng, H.-C. Chang, L. P. McGuinness, M. B. Plenio, B. Naydenov, and F. Jelezko, "Detection of a few metallo-protein molecules using color centers in nanodiamonds," Nano Lett. 13, 3305_3309 (2013).Link
  5. N. D. Lai, O. Faklaris, D. Zheng, V. Jacques, H.-C. Chang, J.-F. Roch, and F. Treussart, "Quenching nitrogen-vacancy center photoluminescence with infrared pulsed laser," New J. Phys. 15, 033030 (2013).Link
  6. J.-H. Hsu, W.-D. Su, K.-L. Yang, Y.-K. Tzeng, and H.-C. Chang, "Non-blinking green emission from single H3 color centers in nanodiamonds," Appl. Phys. Lett. 98, 193116 (2011).Link
  7. Y.-Y. Chen, H. Shu, Y. Kuo, Y.-K. Tzeng, and H.-C. Chang, "Measuring Förster resonance energy transfer between fluorescent nanodiamonds and near-infrared dyes by acceptor photobleaching," Diamond Relat. Mater. 20, 802_807 (2011).Link
  8. Y. Y. Hui,Y.-R. Chang, N. Mohan, T.-S. Lim, Y.-Y. Chen, and H.-C. Chang, "Polarization modulation spectroscopy of single fluorescent nanodiamonds with multiple nitrogen-vacancy centers," J. Phys. Chem. A 115, 1878_1884 (2011). Link
  9. L. Rondin, G. Dantelle, A. Slablab, F. Treussart, P. Bergonzo,S. Perruchas, T. Gacoin, H.-C. Chang, V. Jacques, and J.-F. Roch, "Surface-induced charge state conversion of nitrogen-vacancy defects in nanodiamonds," Phys. Rev. B 82, 115449 (2010). Link
  10. T.-S. Lim, C.-C. Fu, K.-C. Lee, H.-Y. Lee, K. Chen, W.-F. Cheng, W. W. Pai, H.-C. Chang, and W. Fann, "Fluorescence enhancement and lifetime modification of single nanodiamonds near a nanocrystalline silver surface," Phys. Chem. Chem. Phys. 11, 1508_1514 (2009).Link